The selloff in metal, refineries and petrochemical companies contributed the most to the benchmark fall.
TSE's main index TEDPIX lost 536.34 points or 0.22% on Tuesday to end trading at 248,716.3 points.
About 4.3 billion shares valued at 17.57 trillion rials ($137.55 million) changed hands at TSE for the day, according to Financial Tribune.
Trading at TSE and over-the-counter Iran Fara Bourse starts on Saturday and ends Wednesday.
Dashtestan Cement Industries was the biggest winner, as its shares went up 23.83% to 5,379 rials.
Luleh va Mashinsazi Iran, a producer of ductile iron pipes, incurred the biggest loss among all TSE-listed companies and went down 7.93% to 11,147 rials per share.
Mobarakeh Steel Company contributed the most to the benchmark's fall, followed by Mobile Telecommunications Company of Iran, Bandar Abbas Oil Refining Company and Esfahan Oil Refining Company.
Omid Investment Management Group Company gave the biggest boost to the benchmark index, followed by Chadormalu Mining and Industrial Company and Shiraz Petrochemical Company.
The Price Index lost 150.15 points, or 0.22%, to close at 69,652.3.
The First Market Index was down 479.69 points to post 184,011.3. Second Market Index decreased by 684.92 points to reach 491,351.1.
The Industry Index went down by 410.43 points to register 222,270.6. Free Float Index was down 1,016.53 points to hit 278,789.22.
TSE 30 went down 45.45 points to settle at 11,173.9 and TSE 50 ended 30.80 points lower to finish at 10,026.6.
Iran Fara Bourse’s main index IFX gained 3.49 points or 0.11% to close Tuesday trade at 3,222.44.
About 1.65 billion shares and securities valued at 8.86 trillion rials ($69.37 million) were traded at the over-the-counter exchange for the day.