The TSE benchmark, TEDPIX, lost 2,647.54 points, or 0.27%, on Wednesday to end trading at 977,923.47 in the second day of decline.
About 13.01 billion shares valued at 133.06 trillion rials ($842.16 million) changed hands at TSE for the day.
Trading at TSE and over-the-counter Iran Fara Bourse starts on Saturday and ends Wednesday.
Pars Khodro Company was the biggest winner as its shares went up 9.8% to 6,142 rials per share.
Civil Pension Fund Investment Company incurred the biggest loss among all TSE-listed companies and went down 6.16% to 13,081 rials per share.
Persian Gulf Petrochemical Industries Company contributed the most to the benchmark's fall, followed by MAPNA Group, Ghadir Investment Company and Islamic Republic of Iran Shipping Lines Company.
Tehran Oil Refining Company gave the biggest boost to the benchmark index, followed by Golgohar Mining and Industrial Company, Parsian Oil and Gas Development Group Company and Mines and Metals Development Investment Company.
IFX Down 0.14%
Iran Fara Bourse main index, IFX, lost 15.39 points, or 0.14%, to close Wednesday trade at 11,150.28.
About 3.16 billion securities valued at 51.17 trillion rials ($323.87 million) were traded at the over-the-counter exchange.
Esfahan Steel Company had the highest number of traded shares as 417.16 million of its shares worth 2.17 trillion rials ($13.73 million) were traded.
Shahid Tondgooyan Petrochemical Company, Damavand Power Generation Company, Mehr Ayandegan Financial Development Group Company and Iran Office Machines Industries Company had the most negative impact on IFX.
Esfahan Steel Company gave the biggest boost to IFX, followed by Middle East Mines and Mineral Industries Development Holding Company, Jahrom Power Plant Development Company and Iran Cultural Heritage and Tourism Investment Group Company.